Director of Bioinformatics, Biologics Engineering


Jun 2022 – Present Cambridge, UK
Leading the development of an end-to-end data management and analysis strategy and capabilities that will significantly impact the delivery of the novel biologics drugs of the future. This includes building an interdisciplinary team at the intersection of data management, lab automation, computational modelling and machine learning.

Biologics Engineering is responsible for the discovery and optimisation of next generation biological drug candidates for all key therapy areas across AstraZeneca, and for developing in-house biologics discovery platforms and novel drug modalities to address unmet medical needs.

Head of Biological Computation

Microsoft Research

Jul 2010 – Dec 2021 Cambridge, UK
Led research in Biological Computation at Microsoft, developing methods for understanding and programming information processing in biological systems:

Led the creation of academic and industrial partnerships:

Led strategy and communication with senior leadership:

  • Strategic presentations to Microsoft senior leadership to obtain buy-in and financial support for Synthetic Biology research over a 10-year period. Included presentations to Microsoft’s CEO, President, Senior Leadership Team and Board of Directors.
  • Worked extensively with Business Development and Corporate Strategy to create a strategic vision for Synthetic Biology at Microsoft, which enabled sustained investment and growth in Synthetic Biology research.


Microsoft Research

Jul 2007 – Jun 2010 Cambridge, UK
Created the Visual DSD programming language for designing nucleic acid circuits (Royal Society Interface 2009) and jointly created the Visual GEC programming language for designing genetic circuits (Royal Society Interface 2009).

Led a team to develop the Stochastic Pi Machine (SPiM) programming language and used it to model key biological processes, including gene regulatory networks (HFSP Journal 2008), the polymerisation of actin filaments (ENTCS 2009), rho GTP binding proteins (Theoretical Computer Science 2009), Epidermal Growth Factor Receptor networks (BMC Systems Biology 2009) and antigen presentation to T-cells (PLoS Computational Biology 2011).

Postdoctoral Researcher

Microsoft Research

Jul 2005 – Jun 2007 Cambridge, UK
Created the Stochastic Pi Machine (SPiM) programming language for computational modelling of biological systems. The language is based on a formal model of concurrency known as the pi-calculus, and the simulation algorithm is based on stochastic theory of chemical kinetics.

Developed a formal specification of the language syntax and semantics (CMSB 2007). Developed a graphical formalism for models in the language (TCSB 2006) and their execution traces (ENTCS 2008). Used the language for compositional modelling of synthetic gene circuits (TCSB 2006).

Contributing author and co-editor of the 2020 Science Report, highlighted in (Nature 2006). Supervised by Luca Cardelli and Stephen Emmott.



PhD in Computer Science

Department of Computing, Imperial College London

Sep 2000 – Dec 2004 London, UK
Department Scholarship. Overseas Research Scholarship. Winner in the Imperial College Ideas Challenge 2001. Thesis title Specifying and Implementing Secure Mobile Applications in the Channel Ambient System. Supervised by Susan Eisenbach, Nobuko Yoshida and Bashar Nuseibeh.

Master’s degree in Computer Science (Distinction)

Computer Laboratory, University of Cambridge

Oct 1999 – Aug 2000 Cambridge, UK
Award for outstanding dissertation. Scholarship for outstanding examination results. Dissertation title: Implementation of a Mobile Agent Language Based on Pi-Calculus. Supervised by Peter Sewell and Paweł Wojciechowski.

Master’s degree in Electrical and Computer Engineering (First class honours)

Institut National des Sciences Appliquées (INSA)

Sep 1997 – Aug 2000 Toulouse, France
Final year spent at the University of Cambridge as part of a joint honours programme.

Undergraduate Degree in Electrical Engineering (First class honours)

Université Paul Sabatier

Sep 1995 – Jul 1997 Toulouse, France
Award for best examination results.

Secondary Education

Harrison College

Sep 1988 – Jul 1995 Barbados
National scholarship for A-level results. National award for best O-level results.